I'd run the truck on it if I didn't have to mix. It would probably give me another 80whp and who knows how much torque.
I've been DD'ing the neons with E85 for years. It's been easy to put a fuel system together that can handle over 500whp as far as injectors go. Fuel pumps have been a bit of a pain, but things have gotten better with the new Walbro 450 E85 compatible pumps.